Kind

Stages

Staging and state frameworks for CLAD.

Stage
Acute lung allograft dysfunction (ALAD)
Evidence: review-abstract-only; proposed framework
A heterogeneous syndrome of acute lung function decline that the review abstract describes as a chance to characterise graft injury before irreversible fibrosis.
Stage
CLAD stages 0 to 4 by FEV1 relative to baseline
Five severity stages, 0 to 4, defined by current FEV1 as a fraction of the post-transplant baseline.
Stage
ISHLT 2019 CLAD states: Potential, Possible, Probable and Definite
A four-step framework from the 2019 ISHLT consensus that classifies CLAD by the degree and persistence of FEV1 decline.