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CLADsolve

Diagnostic

Hyperpolarised xenon-129 MRI

Evidence level: registry entry; no results posted

A registered technical-development study is evaluating xenon-129 MRI of lung structure and function in lung transplant recipients; CLAD is not named in the registry entry.

As of . Primary source: ClinicalTrials.gov NCT07823010.

Summary

The ClinicalTrials.gov entry NCT07823010, read on 2026-10-10, describes a single-group phase 1/2 study with an estimated 550 participants that aims to develop and optimise proton and xenon gas MRI for regional ventilation, alveolar microstructure and dissolved-phase xenon. The conditions listed are HSCT and lung transplant recipient. CLAD is not named as a condition, no results are posted, and the entry makes no claim about diagnosing CLAD. The record is included because the study uses the technique in lung transplant recipients; its usefulness for CLAD is unknown.

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Known gaps in this record

  • any published result on xenon MRI in CLAD (none found or opened)
  • diagnostic accuracy
  • link to a participating CLADsolve centre

Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.